• World Efforts against covid-19

    THIS SITE WILL ONLY DISPLAY NEWS AND LINKS FROM CREDIBLE SOURCES

    With so much misinformation on social media sites like Facebook and platforms like WhatsApp - we have developed a site only quoting credible sources.

     

    We will only focus on advancements the world is making in the fight to overcome this enemy.

     

    For information on Covid-19 and how to protect yourself please refer to the WHO website below and your country's health agency.

     

    https://www.who.int/emergencies/diseases/novel-coronavirus-2019

     

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  • Latest news

    from around the world

  • Where we are with the most promising vaccines

    Vaccine testing stages - correct as of 03.09.20 - note this represents my own, unscientific, opinion

    1

    Pre-CLINICAL

    Testing of vaccine in non-human subjects

    2

    Phase I

    Testing of vaccine on small group of healthy volunteers

    • Inovio
    • CureVac
    • Imperial College London
    3

    Phase I/II

    Testing of vaccine on c100–300 patients to assess efficacy and side effects

    • CanSino Biologics
    • Sanofi and GlaxoSmithKline
    4

    Phase II/III

    Testing of vaccine on a larger group of patients (c300–3000+) to assess efficacy and side effects

    • Oxford University and AstraZeneca
    • Sinovac
    • Moderna
    • BioNTech and Pfizer
    • China National Biotec
    • Johnson & Johnson (Janssen Pharmaceutical)
    5

    Phase IV

    Vaccine can be released Testing and monitoring will continue

  • Most Promising Vaccines

    What types of vaccines are they?

    DNA Based

    Inovio

    DNA-based vaccines work by inserting a genetically engineered blueprint of viral gene(s) into small DNA molecules (called plasmids) for injection into vaccinated people.Cells take in the DNA plasmids and follow their instructions to build viral proteins, which the immune system recognises as foreign, triggers a immune response that protects against the disease.

     

    No DNA vaccines have been approved for human use to date

    Non-Replicating Viral Vector

    Oxford/AstraZeneca

    CanSino Biologics

    Johnson & Johnson

    Similar to replicating viral vector vaccines -a viral gene is added to a different, non-replicating, virus and delivered to the vaccine recipient.

     

    The first adenovirus vaccine for any disease was approved for Ebola in June 2020.

    RNA-BASED

    Moderna

    BioNTech and - Pfizer

    Imperial College

    CureVac

    Similar to DNA vaccines, these experimental vaccines provide immunity through introduction of genetic material (RNA). RNA vaccines can also be potentially developed more quickly and easily than other vaccines.

     

    No RNA vaccines have been approved for human use but clinical trials have been carried out or are ongoing on mRNA vaccines for influenza, cytomegalovirus, HIV-1, rabies and Zika virus

    INACTIVATED VIRUS

    Sinovac

    China National -Biotec

    A vaccine consisting of the disease-causing virus that has been killed, with heat or chemicals, so it won’t make you sick.

     

    Examples of inactive virus vaccines:

    inactivated poliovirus (IPV) vaccine, whole cell pertussis (whooping cough) vaccine, rabies vaccine and the hepatitis A virus vaccine

    PROTEIN SUBUNIT

     

    Sanofi/

    GlaxoSmithKline

    Rather than introducing whole viruses to an immune system, a fragment of the virus is used to trigger an immune response and stimulate immunity.

     

    Examples of Protein Subunit vaccines: Diphtheria, tetanus, pertussis, hepatitis B

  • Vaccine, Research & Treatments

    LAST 30 UPDATES rolling information on world advances

    NOTE: AS WE ONLY REPORT ON ADVANCES AFTER THEY HAVE BEEN VERIFIED BY MULTIPLE, HIGHLY CREDIBLE, NEWS OUTLETS, THE DATES BELOW MAY BE ONE OR TWO DAYS AFTER the ACTUAL EVENT

    1

    20th October 2020

    UK to begin "challenge" vaccine trials

    2

    9th October 2020

    Remdesivir final data shows it reduces recovery time

    3

    29th September 2020

    Early safety study of Moderna's vaccine shows signs of it working well in older adults

    4

    26th September 2020

    Johnson and Johnson vaccine produced strong immune response in early stage trials

    5

    25th September 2020

    Novavax starts Phase III Covid-19 vaccine trial in UK

    6

    23rd September 2020

    Johnson & Johnsons' Janssen Pharmaceutical moves to phase III

    7

    15th September 2020

    Clinical study to explore the effects of delivering vaccines by inhalation to take place

    8

    13th September 2020

    Oxford/AstraZeneca resumes vaccine trials after 4 day pause

    9

    9th September 2020

    Oxford/AstraZeneca vaccine trial put on hold - do not read into this too much

    10

    3rd September 2020

    Sanofi & GSK move to phase 1/2 trials of their covid-19 vaccine candidate

    11

    2nd September 2020

    Cheap steroid drugs, like hydrocortisone, reduces deaths in the sickest COVID-19 patients

    12

    25th August 2020

    AstraZeneca starts trial of COVID-19 antibody treatment

    13

    24th August 2020

    US allows emergency use of plasma treatment for coronavirus patients

    14

    21st August 2020

    WHO begins talks with Russia as they begin tests on 40,000 people

    15

    11th August 2020

    Russia says it has developed a "vaccine" for covid-19...

    16

    30th July 2020

    Johnson & Johnson vaccine candidate protects monkeys from Covid-19 with one dose

    17

    29th July 2020

    UK signs deal with GSK and Sanofi for 60m doses

    18

    27th July 2020

    Pfizer and BioNTech as well as Moderna begin Phase III trials

    19

    20th July 2020

    Oxford/AstraZeneca vaccine shows positive immune response in early stage data

    20

    14th July 2020

    Moderna will begin Phase III coronavirus vaccine trial on July 27th

    21

    10th July 2020

    Remdesivir data shows it significantly reduced the risk of death

    22

    7th July 2020

    Novavax Announces $1.6 Billion Funding from Operation Warp Speed

    23

    2nd July 2020

    Oxford vaccine team encouraged by immune response

    24

    1st July 2020

    BioNTech and Pfizer’s Covid-19 vaccine trial yields positive results

    25

    30th June 2020

    Bharat Biotech to start human trials of their Covid-19 vaccine candidate

    26

    29th June 2020

    Chinese Military approves use of CanSino's COVID-19 vaccine

    27

    23rd June 2020

    Imperial COVID-19 trial begins

    28

    17th June 2020

    1. CureVac receives regulatory approval from German and Belgian authorities to initiate phase 1 clinical trial

    29

    16th June 2020

    1. Dexamethasone - important trial result for COVID-19

    2.Imperial College to begin human trials for COVID-19 vaccine

    30

    10th June 2020

    Johnson & Johnson coronavirus vaccine trials to begin earlier than expected

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